ctcRbase

Entry Detail

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General Information

Database ID: BRCA03002 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MTCH2 Full Name: mitochondrial carrier 2 Category: mRNA Synonyms: HSPC032|MIMP|SLC25A50 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 47617315 End Site(bp): 47642623 Gene Summary: This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017] External Links: Ensembl ID: ENSG00000109919 HGNC ID: HGNC:17587 Entrez Gene: 23788

Expression Profile of MTCH2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-543 YES YES YES hsa-miR-668-3p YES NO YES hsa-miR-93-5p YES YES NO Display: