| ncRNA Symbol: | TMX2 |
| Full Name: | thioredoxin related transmembrane protein 2 |
| Category: | mRNA |
| Synonyms: | CGI-31|PDIA12|PIG26|TXNDC14 |
| Chromosome: | chr11 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 57712600 | End Site(bp): | 57740973 |
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| Gene Summary: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017] |
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