ctcRbase

Entry Detail

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General Information

Database ID: BRCA03085 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PA2G4 Full Name: proliferation-associated 2G4 Category: mRNA Synonyms: EBP1|HG4-1|p38-2G4 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 56104319 End Site(bp): 56113907 Gene Summary: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000170515 HGNC ID: HGNC:8550 Entrez Gene: 5036

Expression Profile of PA2G4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-223-3p YES YES YES hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-423-5p YES NO YES hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-7-5p YES YES NO Display: