ctcRbase

Entry Detail

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General Information

Database ID: BRCA03101 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: H2AFY Full Name: H2A histone family member Y Category: mRNA Synonyms: H2A.y|H2A/y|H2AF12M|MACROH2A1.1|mH2A1|macroH2A1.2 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 135333900 End Site(bp): 135399914 Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000113648 HGNC ID: HGNC:4740 Entrez Gene: 9555

Expression Profile of H2AFY Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-210-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-365a-3p YES YES YES hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-493-3p YES NO YES hsa-miR-499a-5p YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: