ctcRbase

Entry Detail

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General Information

Database ID: BRCA03168 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PHB Full Name: prohibitin Category: mRNA Synonyms: HEL-215|HEL-S-54e|PHB1 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 49404049 End Site(bp): 49414905 Gene Summary: This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] External Links: Ensembl ID: ENSG00000167085 HGNC ID: HGNC:8912 Entrez Gene: 5245

Expression Profile of PHB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-184 YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO Display: