ctcRbase

Entry Detail

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General Information

Database ID: BRCA03207 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PTK2 Full Name: protein tyrosine kinase 2 Category: mRNA Synonyms: FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 140657900 End Site(bp): 141002216 Gene Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017] External Links: Ensembl ID: ENSG00000169398 HGNC ID: HGNC:9611 Entrez Gene: 5747

Expression Profile of PTK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-139-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-543 YES YES NO hsa-miR-551a YES YES NO hsa-miR-551b-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-93-5p YES YES NO Display: