ctcRbase

Entry Detail

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General Information

Database ID: BRCA03221 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SBDS Full Name: SBDS, ribosome maturation factor Category: mRNA Synonyms: CGI-97|SDS|SWDS Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 66987677 End Site(bp): 66995601 Gene Summary: This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017] External Links: Ensembl ID: ENSG00000126524 HGNC ID: HGNC:19440 Entrez Gene: 51119

Expression Profile of SBDS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-422a YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES NO YES Display: