ctcRbase

Entry Detail

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General Information

Database ID: BRCA03244 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: RBPJ Full Name: recombination signal binding protein for immunoglobulin kappa J region Category: mRNA Synonyms: AOS3|CBF1|IGKJRB|IGKJRB1|KBF2|RBP-J|RBPJK|RBPSUH|SUH|csl Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 26163455 End Site(bp): 26435131 Gene Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013] External Links: Ensembl ID: ENSG00000168214 HGNC ID: HGNC:5724 Entrez Gene: 3516

Expression Profile of RBPJ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-137 NO YES YES hsa-miR-138-5p NO YES YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-195-5p NO YES YES hsa-miR-21-5p YES YES YES hsa-miR-218-5p NO YES YES hsa-miR-223-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-424-5p NO YES YES hsa-miR-490-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p NO YES YES hsa-miR-499a-5p YES YES NO hsa-miR-541-3p YES NO NO hsa-miR-590-5p YES YES YES hsa-miR-599 YES YES NO hsa-miR-654-5p YES NO NO hsa-miR-7-5p YES YES NO Display: