ctcRbase

Entry Detail

---



General Information

Database ID: BRCA03294 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: TLK1 Full Name: tousled like kinase 1 Category: mRNA Synonyms: PKU-beta Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 170990823 End Site(bp): 171231314 Gene Summary: The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000198586 HGNC ID: HGNC:11841 Entrez Gene: 9874

Expression Profile of TLK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181b-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-205-5p YES NO YES hsa-miR-211-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-371a-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-489-3p YES NO YES hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES YES hsa-miR-653-5p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES YES YES Display: