ctcRbase

Entry Detail

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General Information

Database ID: BRCA03320 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: RNPS1 Full Name: RNA binding protein with serine rich domain 1 Category: mRNA Synonyms: E5.1 Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 2253116 End Site(bp): 2268412 Gene Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000205937 HGNC ID: HGNC:10080 Entrez Gene: 10921

Expression Profile of RNPS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES NO YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES NO YES hsa-miR-497-5p YES YES NO hsa-miR-760 YES NO YES Display: