ctcRbase

Entry Detail

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General Information

Database ID: BRCA03326 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: STK3 Full Name: serine/threonine kinase 3 Category: mRNA Synonyms: KRS1|MST2 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 98401403 End Site(bp): 98942827 Gene Summary: This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] External Links: Ensembl ID: ENSG00000104375 HGNC ID: HGNC:11406 Entrez Gene: 6788

Expression Profile of STK3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-9-5p YES YES NO Display: