| ncRNA Symbol: | ATP6AP1 |
| Full Name: | ATPase H+ transporting accessory protein 1 |
| Category: | mRNA |
| Synonyms: | 16A|ATP6IP1|ATP6S1|Ac45|CF2|VATPS1|XAP-3|XAP3 |
| Chromosome: | chrX |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 154428632 | End Site(bp): | 154436516 |
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| Gene Summary: | This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013] |
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