ctcRbase

Entry Detail

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General Information

Database ID: BRCA03369 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TXNL4A Full Name: thioredoxin like 4A Category: mRNA Synonyms: BMKS|DIB1|DIM1|SNRNP15|TXNL4|U5-15kD Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 79970811 End Site(bp): 80033949 Gene Summary: The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] External Links: Ensembl ID: ENSG00000141759 HGNC ID: HGNC:30551 Entrez Gene: 10907

Expression Profile of TXNL4A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-495-3p YES YES NO Display: