ctcRbase

Entry Detail

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General Information

Database ID: BRCA03376 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: GABBR2 Full Name: gamma-aminobutyric acid type B receptor subunit 2 Category: mRNA Synonyms: EIEE59|GABABR2|GPR51|GPRC3B|HG20|HRIHFB2099|NDPLHS Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 98288082 End Site(bp): 98709197 Gene Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010] External Links: Ensembl ID: ENSG00000136928 HGNC ID: HGNC:4507 Entrez Gene: 9568

Expression Profile of GABBR2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-613 YES YES YES Display: