ctcRbase

Entry Detail

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General Information

Database ID: BRCA03387 Cancer Type: breast cancer Dataset: GSE86978 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ODC1 Full Name: ornithine decarboxylase 1 Category: mRNA Synonyms: ODC Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 10439968 End Site(bp): 10448504 Gene Summary: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] External Links: Ensembl ID: ENSG00000115758 HGNC ID: HGNC:8109 Entrez Gene: 4953

Expression Profile of ODC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-187-3p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-328-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-423-5p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-551a YES YES NO Display: