ctcRbase

Entry Detail

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General Information

Database ID: BRCA03388 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: CDH5 Full Name: cadherin 5 Category: mRNA Synonyms: 7B4|CD144 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 66366622 End Site(bp): 66404786 Gene Summary: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015] External Links: Ensembl ID: ENSG00000179776 HGNC ID: HGNC:1764 Entrez Gene: 1003

Expression Profile of CDH5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-143-3p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-145-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-22-3p YES NO YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-873-5p YES YES NO Display: