ctcRbase

Entry Detail

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General Information

Database ID: BRCA03435 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: UBQLN1 Full Name: ubiquilin 1 Category: mRNA Synonyms: DA41|DSK2|PLIC-1|UBQN|XDRP1 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 83659963 End Site(bp): 83708203 Gene Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000135018 HGNC ID: HGNC:12508 Entrez Gene: 29979

Expression Profile of UBQLN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-425-5p YES YES YES hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES YES hsa-miR-93-5p YES YES NO Display: