ctcRbase

Entry Detail

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General Information

Database ID: BRCA03436 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: APRT Full Name: adenine phosphoribosyltransferase Category: mRNA Synonyms: AMP|APRTD Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 88809339 End Site(bp): 88811944 Gene Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000198931 HGNC ID: HGNC:626 Entrez Gene: 353

Expression Profile of APRT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-613 YES YES NO hsa-miR-96-5p YES YES NO Display: