Entry Detail



General Information

Database ID:BRCA03502
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:HSPA1B
Full Name:heat shock protein family A (Hsp70) member 1B
Category:mRNA
Synonyms:HSP70-1|HSP70-1B|HSP70-2|HSP70.1|HSP70.2|HSP72|HSPA1|HSX70
Chromosome:chr6
Strand:+
Coordinate:
Start Site(bp):31827735End Site(bp):31830255
Gene Summary:This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000204388
HGNC ID:HGNC:5233
Entrez Gene:3304



Expression Profile of HSPA1B Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-34a-5p
NO
YES
YES
hsa-miR-34c-5p
NO
YES
YES
hsa-miR-449a
NO
YES
YES
hsa-miR-449b-5p
NO
YES
YES
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