ctcRbase

Entry Detail

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General Information

Database ID: BRCA03503 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: FUS Full Name: FUS RNA binding protein Category: mRNA Synonyms: ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 31180110 End Site(bp): 31194871 Gene Summary: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000089280 HGNC ID: HGNC:4010 Entrez Gene: 2521

Expression Profile of FUS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7b-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-383-5p YES YES NO hsa-miR-495-3p YES YES NO Display: