ctcRbase

Entry Detail

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General Information

Database ID: BRCA03508 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: TRAF4 Full Name: TNF receptor associated factor 4 Category: mRNA Synonyms: CART1|MLN62|RNF83 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 28743984 End Site(bp): 28750958 Gene Summary: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000076604 HGNC ID: HGNC:12034 Entrez Gene: 9618

Expression Profile of TRAF4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-17-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-331-3p YES NO YES hsa-miR-339-5p YES YES NO hsa-miR-346 YES YES YES hsa-miR-370-3p YES YES YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-760 YES NO YES hsa-miR-93-5p YES YES NO Display: