ctcRbase

Entry Detail

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General Information

Database ID: BRCA03509 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: BSCL2 Full Name: BSCL2, seipin lipid droplet biogenesis associated Category: mRNA Synonyms: GNG3LG|HMN5|PELD|SPG17 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 62690275 End Site(bp): 62709845 Gene Summary: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000168000 HGNC ID: HGNC:15832 Entrez Gene: 26580

Expression Profile of BSCL2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-346 NO YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-613 YES YES YES hsa-miR-93-5p YES YES NO Display: