ctcRbase

Entry Detail

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General Information

Database ID: BRCA03512 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CAMLG Full Name: calcium modulating ligand Category: mRNA Synonyms: CAML|GET2 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 134738501 End Site(bp): 134752160 Gene Summary: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000164615 HGNC ID: HGNC:1471 Entrez Gene: 819

Expression Profile of CAMLG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-411-5p NO YES YES hsa-miR-425-5p YES YES NO hsa-miR-433-3p NO YES YES hsa-miR-519d-3p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-93-5p YES YES NO Display: