ctcRbase

Entry Detail

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General Information

Database ID: BRCA03558 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MMADHC Full Name: metabolism of cobalamin associated D Category: mRNA Synonyms: C2orf25|CL25022|cblD Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 149569634 End Site(bp): 149587816 Gene Summary: This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov 2008] External Links: Ensembl ID: ENSG00000168288 HGNC ID: HGNC:25221 Entrez Gene: 27249

Expression Profile of MMADHC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-429 YES YES NO hsa-miR-543 YES YES NO hsa-miR-7-5p YES YES NO Display: