ctcRbase

Entry Detail

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General Information

Database ID: BRCA03572 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SVIP Full Name: small VCP interacting protein Category: mRNA Synonyms: - Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 22813799 End Site(bp): 22830299 Gene Summary: Endoplasmic reticulum-associated degradation (ERAD) is the pathway by which misfolded proteins in the endoplasmic reticulum are targeted to the proteasome for degradation. Multiple specialized proteins interact with one another during ERAD to complete this process. The protein encoded by this gene is an inhibitor of ERAD, functioning to disrupt the interaction of these protein components. This downregulation of ERAD may be needed to protect the cell from overactive protein degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000198168 HGNC ID: HGNC:25238 Entrez Gene: 258010

Expression Profile of SVIP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES NO YES hsa-miR-1271-5p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-205-5p YES NO YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-383-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-96-5p YES YES NO Display: