| ncRNA Symbol: | ANKS1B |
| Full Name: | ankyrin repeat and sterile alpha motif domain containing 1B |
| Category: | mRNA |
| Synonyms: | AIDA|AIDA-1|ANKS2|EB-1|EB1|cajalin-2 |
| Chromosome: | chr12 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 98726457 | End Site(bp): | 99984654 | |
| Gene Summary: | This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011] |
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