ctcRbase

Entry Detail

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General Information

Database ID: BRCA03688 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: NOP10 Full Name: NOP10 ribonucleoprotein Category: mRNA Synonyms: DKCB1|NOLA3|NOP10P Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 34341713 End Site(bp): 34343177 Gene Summary: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000182117 HGNC ID: HGNC:14378 Entrez Gene: 55505

Expression Profile of NOP10 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-194-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-377-3p YES YES NO Display: