ctcRbase

Entry Detail

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General Information

Database ID: BRCA03695 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: EIF2S2 Full Name: eukaryotic translation initiation factor 2 subunit beta Category: mRNA Synonyms: EIF2|EIF2B|EIF2beta|PPP1R67|eIF-2-beta Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 34088298 End Site(bp): 34112332 Gene Summary: Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000125977 HGNC ID: HGNC:3266 Entrez Gene: 8894

Expression Profile of EIF2S2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES NO YES hsa-miR-187-3p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-362-5p YES NO YES hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-421 YES YES YES hsa-miR-424-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-505-3p YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-96-5p YES YES NO hsa-miR-98-5p YES YES YES Display: