ctcRbase

Entry Detail

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General Information

Database ID: BRCA03719 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ARHGDIA Full Name: Rho GDP dissociation inhibitor alpha Category: mRNA Synonyms: GDIA1|HEL-S-47e|NPHS8|RHOGDI|RHOGDI-1 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 81867721 End Site(bp): 81871406 Gene Summary: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000141522 HGNC ID: HGNC:678 Entrez Gene: 396

Expression Profile of ARHGDIA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-184 YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-423-5p YES NO NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES NO YES Display: