ctcRbase

Entry Detail

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General Information

Database ID: BRCA03785 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: NEDD4 Full Name: neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase Category: mRNA Synonyms: NEDD4-1|RPF1 Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 55826922 End Site(bp): 55993746 Gene Summary: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000069869 HGNC ID: HGNC:7727 Entrez Gene: 4734

Expression Profile of NEDD4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-122-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-7-5p YES YES NO hsa-miR-9-5p YES YES YES hsa-miR-96-5p YES YES NO Display: