| ncRNA Symbol: | RNF19A | | Full Name: | ring finger protein 19A, RBR E3 ubiquitin protein ligase | | Category: | mRNA | | Synonyms: | RNF19 | | Chromosome: | chr8 | | Strand: | - | | Coordinate: | | Start Site(bp): | 100257060 | End Site(bp): | 100336218 | | | Gene Summary: | This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | | External Links: | |
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