ctcRbase

Entry Detail

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General Information

Database ID: BRCA03804 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: UBE2V1 Full Name: ubiquitin conjugating enzyme E2 V1 Category: mRNA Synonyms: CIR1|CROC-1|CROC1|UBE2V|UEV-1|UEV1|UEV1A Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 50081124 End Site(bp): 50115959 Gene Summary: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000244687 HGNC ID: HGNC:12494 Entrez Gene: 7335

Expression Profile of UBE2V1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-128-3p YES NO YES hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-214-3p YES NO NO hsa-miR-218-5p YES YES NO hsa-miR-219a-5p YES NO YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-455-5p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-499a-5p YES YES YES hsa-miR-503-5p YES NO NO Display: