ctcRbase

Entry Detail

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General Information

Database ID: BRCA03875 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PDIA6 Full Name: protein disulfide isomerase family A member 6 Category: mRNA Synonyms: ERP5|P5|TXNDC7 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 10783391 End Site(bp): 10837977 Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016] External Links: Ensembl ID: ENSG00000143870 HGNC ID: HGNC:30168 Entrez Gene: 10130

Expression Profile of PDIA6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-216b-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO Display: