| ncRNA Symbol: | VPS35 | | Full Name: | VPS35, retromer complex component | | Category: | mRNA | | Synonyms: | MEM3|PARK17 | | Chromosome: | chr16 | | Strand: | - | | Coordinate: | | Start Site(bp): | 46656132 | End Site(bp): | 46689518 | | | Gene Summary: | This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008] | | External Links: | |
|