ctcRbase

Entry Detail

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General Information

Database ID: BRCA03916 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: CCNDBP1 Full Name: cyclin D1 binding protein 1 Category: mRNA Synonyms: DIP1|GCIP|HHM Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 43185118 End Site(bp): 43197176 Gene Summary: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009] External Links: Ensembl ID: ENSG00000166946 HGNC ID: HGNC:1587 Entrez Gene: 23582

Expression Profile of CCNDBP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-217 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-384 YES YES NO hsa-miR-9-5p YES YES YES Display: