Entry Detail



General Information

Database ID:BRCA03961
Cancer Type:breast cancer
Dataset:GSE75367
CTCs/CTM Isolation Method:micromanipulation immunofluorescence



Gene Information

ncRNA Symbol:SOD2
Full Name:superoxide dismutase 2
Category:mRNA
Synonyms:IPO-B|IPOB|MNSOD|MVCD6|Mn-SOD
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):159669057End Site(bp):159762529
Gene Summary:This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
External Links:
Ensembl ID:ENSG00000112096
HGNC ID:HGNC:11180
Entrez Gene:6648



Expression Profile of SOD2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-132-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-192-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-215-5p
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-22-3p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-324-5p
YES
YES
NO
hsa-miR-330-3p
YES
NO
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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