ctcRbase

Entry Detail

---



General Information

Database ID: BRCA03962 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SRP72 Full Name: signal recognition particle 72 Category: mRNA Synonyms: BMFF|BMFS1|HEL103 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 56466915 End Site(bp): 56503680 Gene Summary: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012] External Links: Ensembl ID: ENSG00000174780 HGNC ID: HGNC:11303 Entrez Gene: 6731

Expression Profile of SRP72 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-613 YES YES NO Display: