ctcRbase

Entry Detail

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General Information

Database ID: BRCA03976 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: RHEB Full Name: Ras homolog, mTORC1 binding Category: mRNA Synonyms: RHEB2 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 151466012 End Site(bp): 151520120 Gene Summary: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000106615 HGNC ID: HGNC:10011 Entrez Gene: 6009

Expression Profile of RHEB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-22-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-365a-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-495-3p YES YES YES Display: