ctcRbase

Entry Detail

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General Information

Database ID: BRCA03987 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: KIDINS220 Full Name: kinase D interacting substrate 220 Category: mRNA Synonyms: ARMS|SINO Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 8721081 End Site(bp): 8837630 Gene Summary: This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] External Links: Ensembl ID: ENSG00000134313 HGNC ID: HGNC:29508 Entrez Gene: 57498

Expression Profile of KIDINS220 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-96-5p YES YES NO Display: