ctcRbase

Entry Detail

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General Information

Database ID: BRCA04014 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MDK Full Name: midkine Category: mRNA Synonyms: ARAP|MK|NEGF2 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 46380756 End Site(bp): 46383837 Gene Summary: This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012] External Links: Ensembl ID: ENSG00000110492 HGNC ID: HGNC:6972 Entrez Gene: 4192

Expression Profile of MDK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-625-5p YES NO NO Display: