ctcRbase

Entry Detail

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General Information

Database ID: BRCA04031 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: AAK1 Full Name: AP2 associated kinase 1 Category: mRNA Synonyms: - Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 69457997 End Site(bp): 69674349 Gene Summary: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000115977 HGNC ID: HGNC:19679 Entrez Gene: 22848

Expression Profile of AAK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-124-3p YES NO YES hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-139-5p YES NO YES hsa-miR-149-5p YES NO YES hsa-miR-153-3p YES NO YES hsa-miR-155-5p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-185-5p YES NO YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-24-3p YES NO YES hsa-miR-28-5p YES NO YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-338-3p YES NO YES hsa-miR-361-5p YES NO YES hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-378a-3p YES NO YES hsa-miR-382-5p YES NO YES hsa-miR-384 YES NO YES hsa-miR-422a YES NO YES hsa-miR-429 YES NO YES hsa-miR-454-3p YES NO YES hsa-miR-455-3p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-582-5p YES NO YES hsa-miR-708-5p YES NO YES hsa-miR-93-5p YES NO YES hsa-miR-98-5p YES NO YES Display: