ctcRbase

Entry Detail

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General Information

Database ID: BRCA04095 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: MAX Full Name: MYC associated factor X Category: mRNA Synonyms: bHLHd4 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 65006174 End Site(bp): 65102695 Gene Summary: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] External Links: Ensembl ID: ENSG00000125952 HGNC ID: HGNC:6913 Entrez Gene: 4149

Expression Profile of MAX Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-148a-3p YES NO YES hsa-miR-148b-3p YES NO YES hsa-miR-152-3p YES NO YES hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-206 YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-24-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-335-5p YES YES YES hsa-miR-339-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-613 YES YES NO hsa-miR-615-3p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES NO Display: