ctcRbase

Entry Detail

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General Information

Database ID: BRCA04202 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PAIP2B Full Name: poly(A) binding protein interacting protein 2B Category: mRNA Synonyms: - Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 71182739 End Site(bp): 71227083 Gene Summary: Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000124374 HGNC ID: HGNC:29200 Entrez Gene: 400961

Expression Profile of PAIP2B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-128-3p YES NO YES hsa-miR-17-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-299-3p YES NO YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-454-3p YES YES NO hsa-miR-491-5p YES NO YES hsa-miR-499a-5p YES NO YES hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO Display: