ctcRbase

Entry Detail

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General Information

Database ID: BRCA04220 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PIGP Full Name: phosphatidylinositol glycan anchor biosynthesis class P Category: mRNA Synonyms: DCRC|DCRC-S|DSCR5|DSRC|EIEE55|PIG-P Chromosome: chr21 Strand: - Coordinate: Start Site(bp): 37059170 End Site(bp): 37073170 Gene Summary: This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000185808 HGNC ID: HGNC:3046 Entrez Gene: 51227

Expression Profile of PIGP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-613 YES YES NO Display: