ctcRbase

Entry Detail

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General Information

Database ID: BRCA04264 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: CBX3 Full Name: chromobox 3 Category: mRNA Synonyms: HECH|HP1-GAMMA|HP1Hs-gamma Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 26201162 End Site(bp): 26213356 Gene Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000122565 HGNC ID: HGNC:1553 Entrez Gene: 11335

Expression Profile of CBX3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-142-5p YES NO YES hsa-miR-154-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-29a-3p NO YES YES hsa-miR-29b-3p NO YES YES hsa-miR-29c-3p NO YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-370-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-378a-3p NO YES YES hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES NO YES hsa-miR-433-3p NO YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-543 YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-873-5p YES YES NO Display: