Entry Detail



General Information

Database ID:BRCA04303
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:GANAB
Full Name:glucosidase II alpha subunit
Category:mRNA
Synonyms:G2AN|GIIA|GLUII|PKD3
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):62624826End Site(bp):62646726
Gene Summary:This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
External Links:
Ensembl ID:ENSG00000089597
HGNC ID:HGNC:4138
Entrez Gene:23193



Expression Profile of GANAB Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-136-5p
YES
NO
YES
hsa-miR-145-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-193a-5p
YES
NO
YES
hsa-miR-199a-5p
YES
YES
YES
hsa-miR-199b-5p
YES
YES
YES
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-324-5p
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-483-3p
YES
NO
YES
hsa-miR-488-3p
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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