ctcRbase

Entry Detail

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General Information

Database ID: BRCA04346 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SUMF2 Full Name: sulfatase modifying factor 2 Category: mRNA Synonyms: pFGE Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 56064002 End Site(bp): 56080670 Gene Summary: The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000129103 HGNC ID: HGNC:20415 Entrez Gene: 25870

Expression Profile of SUMF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-542-3p YES YES NO Display: