ctcRbase

Entry Detail

---



General Information

Database ID: BRCA04350 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CLK1 Full Name: CDC like kinase 1 Category: mRNA Synonyms: CLK|CLK/STY|STY Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 200853009 End Site(bp): 200864744 Gene Summary: This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] External Links: Ensembl ID: ENSG00000013441 HGNC ID: HGNC:2068 Entrez Gene: 1195

Expression Profile of CLK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-151a-3p YES NO YES hsa-miR-183-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-495-3p YES YES NO Display: