ctcRbase

Entry Detail

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General Information

Database ID: BRCA04437 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SDHD Full Name: succinate dehydrogenase complex subunit D Category: mRNA Synonyms: CBT1|CII-4|CWS3|PGL|PGL1|QPs3|SDH4|cybS Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 112086773 End Site(bp): 112120013 Gene Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] External Links: Ensembl ID: ENSG00000204370 HGNC ID: HGNC:10683 Entrez Gene: 6392

Expression Profile of SDHD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-204-5p YES YES YES hsa-miR-210-3p YES YES NO hsa-miR-211-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-874-3p YES YES NO Display: