Entry Detail


General Information

Database ID:BRCA04480
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:SRSF10
Full Name:serine and arginine rich splicing factor 10
Category:mRNA
Synonyms:FUSIP1|FUSIP2|NSSR|PPP1R149|SFRS13|SFRS13A|SRp38|SRrp40|TASR|TASR1|TASR2
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):23964804End Site(bp):23980927
Gene Summary:This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
External Links:
Ensembl ID:ENSG00000188529
HGNC ID:HGNC:16713
Entrez Gene:10772



Expression Profile of SRSF10 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-139-5p
NO
YES
YES
hsa-miR-141-3p
NO
YES
YES
hsa-miR-144-3p
NO
YES
YES
hsa-miR-153-3p
NO
YES
YES
hsa-miR-183-5p
NO
YES
YES
hsa-miR-200a-3p
NO
YES
YES
hsa-miR-200b-3p
NO
YES
YES
hsa-miR-200c-3p
NO
YES
YES
hsa-miR-221-3p
NO
YES
YES
hsa-miR-222-3p
NO
YES
YES
hsa-miR-22-3p
NO
YES
YES
hsa-miR-31-5p
NO
YES
YES
hsa-miR-346
NO
YES
YES
hsa-miR-378a-3p
NO
YES
YES
hsa-miR-421
NO
YES
YES
hsa-miR-422a
NO
YES
YES
hsa-miR-429
NO
YES
YES
hsa-miR-448
NO
YES
YES
hsa-miR-495-3p
NO
YES
YES
hsa-miR-543
NO
YES
YES
hsa-miR-9-5p
NO
YES
YES
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